Our Publications

Complete list of published work linked to our publications can be found here:

https://www.ncbi.nlm.nih.gov/myncbi/pavel.petukhov.1/bibliography/public/

1.            Fata F, Silvestri I, Ardini M, Ippoliti R, Di Leandro L, Demitri N, Polentarutti M, Di Matteo A, Lyu H, Thatcher GRJ, Petukhov PA, Williams DL, Angelucci F. Probing the Surface of a Parasite Drug Target Thioredoxin Glutathione Reductase Using Small Molecule Fragments. ACS Infect Dis. 2021;7(7):1932-44. Epub 20210505. doi: 10.1021/acsinfecdis.0c00909. PubMed PMID: 33950676; PMCID: PMC8273128.

2.            Popova IA, Lubbe L, Petukhov PA, Kalantarov GF, Trakht IN, Chernykh ER, Leplina OY, Lyubimov AV, Garcia JGN, Dudek SM, Sturrock ED, Danilov SM. Epitope mapping of novel monoclonal antibodies to human angiotensin I-converting enzyme. Protein Sci. 2021;30(8):1577-93. Epub 20210511. doi: 10.1002/pro.4091. PubMed PMID: 33931897; PMCID: PMC8284578.

3.            Bertels Z, Singh H, Dripps I, Siegersma K, Tipton AF, Witkowski WD, Sheets Z, Shah P, Conway C, Mangutov E, Ao M, Petukhova V, Karumudi B, Petukhov PA, Baca SM, Rasenick MM, Pradhan AA. Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition. Elife. 2021;10. Epub 20210415. doi: 10.7554/eLife.63076. PubMed PMID: 33856345; PMCID: PMC8147088.

4.            Taha TY, Anirudhan V, Limothai U, Loeb DD, Petukhov PA, McLachlan A. Modulation of hepatitis B virus pregenomic RNA stability and splicing by histone deacetylase 5 enhances viral biosynthesis. PLoS Pathog. 2020;16(8):e1008802. Epub 20200821. doi: 10.1371/journal.ppat.1008802. PubMed PMID: 32822428; PMCID: PMC7467325.

5.            Danilov SM, Jain MS, Petukhov PA, Goldman C, DiSanto-Rose M, Vancavage R, Francuzevitch LY, Samokhodskaya LM, Kamalov AA, Arbieva ZH, Sturrock ED, Dudek SM, Judson MA. Novel ACE mutations mimicking sarcoidosis by increasing blood ACE levels. Transl Res. 2021;230:5-20. Epub 20200726. doi: 10.1016/j.trsl.2020.07.010. PubMed PMID: 32726712.

6.            Lyu H, Petukhov PA, Banta PR, Jadhav A, Lea WA, Cheng Q, Arner ESJ, Simeonov A, Thatcher GRJ, Angelucci F, Williams DL. Characterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis. ACS Infect Dis. 2020;6(3):393-405. Epub 20200124. doi: 10.1021/acsinfecdis.9b00354. PubMed PMID: 31939288; PMCID: PMC7072008.

7.            Silvestri I, Lyu H, Fata F, Banta PR, Mattei B, Ippoliti R, Bellelli A, Pitari G, Ardini M, Petukhova V, Thatcher GRJ, Petukhov PA, Williams DL, Angelucci F. Ectopic suicide inhibition of thioredoxin glutathione reductase. Free Radic Biol Med. 2020;147:200-11. Epub 20191220. doi: 10.1016/j.freeradbiomed.2019.12.019. PubMed PMID: 31870799; PMCID: PMC7583042.

8.            Taha TY, Aboukhatwa SM, Knopp RC, Ikegaki N, Abdelkarim H, Neerasa J, Lu Y, Neelarapu R, Hanigan TW, Thatcher GRJ, Petukhov PA. Correction to Design, Synthesis, and Biological Evaluation of Tetrahydroisoquinoline-Based Histone Deacetylase 8 Selective Inhibitors. ACS Med Chem Lett. 2019;10(9):1358. Epub 20190802. doi: 10.1021/acsmedchemlett.9b00336. PubMed PMID: 31531211; PMCID: PMC6746072.

9.            Aboukhatwa SM, Hanigan TW, Taha TY, Neerasa J, Ranjan R, El-Bastawissy EE, Elkersh MA, El-Moselhy TF, Frasor J, Mahmud N, McLachlan A, Petukhov PA. Structurally Diverse Histone Deacetylase Photoreactive Probes: Design, Synthesis, and Photolabeling Studies in Live Cells and Tissue. ChemMedChem. 2019;14(11):1096-107. Epub 20190410. doi: 10.1002/cmdc.201900114. PubMed PMID: 30921497; PMCID: PMC6548601.

10.        Li J, Kim K, Jeong SY, Chiu J, Xiong B, Petukhov PA, Dai X, Li X, Andrews RK, Du X, Hogg PJ, Cho J. Platelet Protein Disulfide Isomerase Promotes Glycoprotein Ibalpha-Mediated Platelet-Neutrophil Interactions Under Thromboinflammatory Conditions. Circulation. 2019;139(10):1300-19. doi: 10.1161/CIRCULATIONAHA.118.036323. PubMed PMID: 30586735; PMCID: PMC6464389.

11.        Silvestri I, Lyu H, Fata F, Boumis G, Miele AE, Ardini M, Ippoliti R, Bellelli A, Jadhav A, Lea WA, Simeonov A, Cheng Q, Arner ESJ, Thatcher GRJ, Petukhov PA, Williams DL, Angelucci F. Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. ACS Chem Biol. 2018;13(8):2190-202. Epub 20180611. doi: 10.1021/acschembio.8b00349. PubMed PMID: 29800515; PMCID: PMC6905387.

12.        Hanigan TW, Danes JM, Taha TY, Frasor J, Petukhov PA. Histone deacetylase inhibitor-based chromatin precipitation for identification of targeted genomic loci. J Biol Methods. 2018;5(1). doi: 10.14440/jbm.2018.216. PubMed PMID: 29682593; PMCID: PMC5909381.

13.        Bhattacharjee A, Sinha A, Ratia K, Yin L, Delgado-Rivera L, Petukhov PA, Thatcher GRJ, Wardrop DJ. 2-Arylidene Hydrazinecarbodithioates as Potent, Selective Inhibitors of Cystathionine gamma-Lyase (CSE). ACS Med Chem Lett. 2017;8(12):1241-5. Epub 20171121. doi: 10.1021/acsmedchemlett.7b00313. PubMed PMID: 29259741; PMCID: PMC5733271.

14.        Abdelkarim H, Neelarapu R, Madriaga A, Vaidya AS, Kastrati I, Karumudi B, Wang YT, Taha TY, Thatcher GRJ, Frasor J, Petukhov PA. Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Amine-based Histone Deacetylase Inhibitors. ChemMedChem. 2017;12(24):2030-43. Epub 20171130. doi: 10.1002/cmdc.201700449. PubMed PMID: 29080240; PMCID: PMC5881582.

15.        Hanigan TW, Taha TY, Aboukhatwa SM, Frasor J, Petukhov PA. Scaffold dependent histone deacetylase (HDAC) inhibitor induced re-equilibration of the subcellular localization and post-translational modification state of class I HDACs. PLoS One. 2017;12(10):e0186620. Epub 20171018. doi: 10.1371/journal.pone.0186620. PubMed PMID: 29045501; PMCID: PMC5646865.

16.        Hanigan TW, Aboukhatwa SM, Taha TY, Frasor J, Petukhov PA. Divergent JNK Phosphorylation of HDAC3 in Triple-Negative Breast Cancer Cells Determines HDAC Inhibitor Binding and Selectivity. Cell Chem Biol. 2017;24(11):1356-67 e8. Epub 20170921. doi: 10.1016/j.chembiol.2017.08.015. PubMed PMID: 28943357; PMCID: PMC5693607.

17.        Taha TY, Aboukhatwa SM, Knopp RC, Ikegaki N, Abdelkarim H, Neerasa J, Lu Y, Neelarapu R, Hanigan TW, Thatcher GRJ, Petukhov PA. Design, Synthesis, and Biological Evaluation of Tetrahydroisoquinoline-Based Histone Deacetylase 8 Selective Inhibitors. ACS Med Chem Lett. 2017;8(8):824-9. Epub 20170801. doi: 10.1021/acsmedchemlett.7b00126. PubMed PMID: 28835796; PMCID: PMC5554898.

18.        Petiwala SM, Li G, Bosland MC, Lantvit DD, Petukhov PA, Johnson JJ. Carnosic acid promotes degradation of the androgen receptor and is regulated by the unfolded protein response pathway in vitro and in vivo. Carcinogenesis. 2016;37(8):827-38. Epub 20160607. doi: 10.1093/carcin/bgw052. PubMed PMID: 27267997.

19.        Li G, Petiwala SM, Yan M, Won JH, Petukhov PA, Johnson JJ. Gartanin, an isoprenylated xanthone from the mangosteen fruit (Garcinia mangostana), is an androgen receptor degradation enhancer. Mol Nutr Food Res. 2016;60(6):1458-69. Epub 20160519. doi: 10.1002/mnfr.201600037. PubMed PMID: 27019217.

20.        Fa M, Zhang H, Staniszewski A, Saeed F, Shen LW, Schiefer IT, Siklos MI, Tapadar S, Litosh VA, Libien J, Petukhov PA, Teich AF, Thatcher GR, Arancio O. Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease. J Alzheimers Dis. 2016;49(3):707-21. doi: 10.3233/JAD-150618. PubMed PMID: 26484927; PMCID: PMC8962836.

21.        Toh MF, Mendonca E, Eddie SL, Endsley MP, Lantvit DD, Petukhov PA, Burdette JE. Kaempferol Exhibits Progestogenic Effects in Ovariectomized Rats. J Steroids Horm Sci. 2014;5(3):136. doi: 10.4172/2157-7536.1000136. PubMed PMID: 25844270; PMCID: PMC4382015.

22.        Abdelkarim H, Brunsteiner M, Neelarapu R, Bai H, Madriaga A, van Breemen RB, Blond SY, Gaponenko V, Petukhov PA. Photoreactive "nanorulers" detect a novel conformation of full length HDAC3-SMRT complex in solution. ACS Chem Biol. 2013;8(11):2538-49. Epub 20131002. doi: 10.1021/cb400601g. PubMed PMID: 24010878; PMCID: PMC3880688.

23.        Patel HK, Siklos MI, Abdelkarim H, Mendonca EL, Vaidya A, Petukhov PA, Thatcher GR. A chimeric SERM-histone deacetylase inhibitor approach to breast cancer therapy. ChemMedChem. 2014;9(3):602-13. Epub 20130816. doi: 10.1002/cmdc.201300270. PubMed PMID: 23956109; PMCID: PMC3962780.

24.        Schiefer IT, Tapadar S, Litosh V, Siklos M, Scism R, Wijewickrama GT, Chandrasena EP, Sinha V, Tavassoli E, Brunsteiner M, Fa M, Arancio O, Petukhov P, Thatcher GR. Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors. J Med Chem. 2013;56(15):6054-68. Epub 20130722. doi: 10.1021/jm4006719. PubMed PMID: 23834438; PMCID: PMC3962784.

25.        Vaidya AS, Neelarapu R, Madriaga A, Bai H, Mendonca E, Abdelkarim H, van Breemen RB, Blond SY, Petukhov PA. Novel histone deacetylase 8 ligands without a zinc chelating group: exploring an 'upside-down' binding pose. Bioorg Med Chem Lett. 2012;22(21):6621-7. Epub 20120907. doi: 10.1016/j.bmcl.2012.08.104. PubMed PMID: 23010266; PMCID: PMC3472134.

26.        Yu X, Sainz B, Jr., Petukhov PA, Uprichard SL. Identification of hepatitis C virus inhibitors targeting different aspects of infection using a cell-based assay. Antimicrob Agents Chemother. 2012;56(12):6109-20. Epub 20120904. doi: 10.1128/AAC.01413-12. PubMed PMID: 22948883; PMCID: PMC3497158.

27.        Neelarapu R, Petukhov PA. A One-Pot Selective Synthesis of N-Boc Protected Secondary Amines: Tandem Direct Reductive Amination/N-Boc Protection. Tetrahedron. 2012;68(35):7056-62. Epub 20120622. doi: 10.1016/j.tet.2012.06.055. PubMed PMID: 22844160; PMCID: PMC3404846.

28.        Vaidya AS, Karumudi B, Mendonca E, Madriaga A, Abdelkarim H, van Breemen RB, Petukhov PA. Design, synthesis, modeling, biological evaluation and photoaffinity labeling studies of novel series of photoreactive benzamide probes for histone deacetylase 2. Bioorg Med Chem Lett. 2012;22(15):5025-30. Epub 20120618. doi: 10.1016/j.bmcl.2012.06.017. PubMed PMID: 22771007; PMCID: PMC3401313.

29.        Brunsteiner M, Petukhov PA. Insights from comprehensive multiple receptor docking to HDAC8. J Mol Model. 2012;18(8):3927-39. Epub 20120320. doi: 10.1007/s00894-011-1297-8. PubMed PMID: 22431224; PMCID: PMC3565472.

30.        Danilov SM, Gordon K, Nesterovitch AB, Lunsdorf H, Chen Z, Castellon M, Popova IA, Kalinin S, Mendonca E, Petukhov PA, Schwartz DE, Minshall RD, Sturrock ED. An angiotensin I-converting enzyme mutation (Y465D) causes a dramatic increase in blood ACE via accelerated ACE shedding. PLoS One. 2011;6(10):e25952. Epub 20111005. doi: 10.1371/journal.pone.0025952. PubMed PMID: 21998728; PMCID: PMC3187827.

31.        Nesterovitch AB, Hoffman MD, Simon M, Petukhov PA, Tharp MD, Glant TT. Mutations in the PSTPIP1 gene and aberrant splicing variants in patients with pyoderma gangrenosum. Clin Exp Dermatol. 2011;36(8):889-95. Epub 20110725. doi: 10.1111/j.1365-2230.2011.04137.x. PubMed PMID: 21790734.

32.        Neelarapu R, Holzle DL, Velaparthi S, Bai H, Brunsteiner M, Blond SY, Petukhov PA. Design, synthesis, docking, and biological evaluation of novel diazide-containing isoxazole- and pyrazole-based histone deacetylase probes. J Med Chem. 2011;54(13):4350-64. Epub 20110602. doi: 10.1021/jm2001025. PubMed PMID: 21548582; PMCID: PMC3466118.

33.        He B, Velaparthi S, Pieffet G, Pennington C, Mahesh A, Holzle DL, Brunsteiner M, van Breemen R, Blond SY, Petukhov PA. Binding ensemble profiling with photoaffinity labeling (BEProFL) approach: mapping the binding poses of HDAC8 inhibitors. J Med Chem. 2009;52(22):7003-13. doi: 10.1021/jm9005077. PubMed PMID: 19886628; PMCID: PMC2789734.

34.        Pieffet G, Petukhov PA. Parameterization of aromatic azido groups: application as photoaffinity probes in molecular dynamics studies. J Mol Model. 2009;15(11):1291-7. Epub 20090314. doi: 10.1007/s00894-009-0488-z. PubMed PMID: 19288146; PMCID: PMC2745498.

35.        Chirapu SR, Pachaiyappan B, Nural HF, Cheng X, Yuan H, Lankin DC, Abdul-Hay SO, Thatcher GR, Shen Y, Kozikowski AP, Petukhov PA. Molecular modeling, synthesis, and activity studies of novel biaryl and fused-ring BACE1 inhibitors. Bioorg Med Chem Lett. 2009;19(1):264-74. Epub 20081025. doi: 10.1016/j.bmcl.2008.10.096. PubMed PMID: 19013792; PMCID: PMC2643073.

36.        Chang M, Overk CR, Kastrati I, Peng KW, Yao P, Qin ZH, Petukhov P, Bolton JL, Thatcher GR. Estrogenic activity of the equine estrogen metabolite, 4-methoxyequilenin. Adv Exp Med Biol. 2008;617:601-7. doi: 10.1007/978-0-387-69080-3_62. PubMed PMID: 18497087.

37.        Zaheer-ul H, Uddin R, Yuan H, Petukhov PA, Choudhary MI, Madura JD. Receptor-based modeling and 3D-QSAR for a quantitative production of the butyrylcholinesterase inhibitors based on genetic algorithm. J Chem Inf Model. 2008;48(5):1092-103. Epub 20080429. doi: 10.1021/ci8000056. PubMed PMID: 18444627.

38.        Velaparthi S, Brunsteiner M, Uddin R, Wan B, Franzblau SG, Petukhov PA. 5-tert-butyl-N-pyrazol-4-yl-4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxamide derivatives as novel potent inhibitors of Mycobacterium tuberculosis pantothenate synthetase: initiating a quest for new antitubercular drugs. J Med Chem. 2008;51(7):1999-2002. Epub 20080313. doi: 10.1021/jm701372r. PubMed PMID: 18335974.

39.        Gills JJ, Castillo SS, Zhang C, Petukhov PA, Memmott RM, Hollingshead M, Warfel N, Han J, Kozikowski AP, Dennis PA. Phosphatidylinositol ether lipid analogues that inhibit AKT also independently activate the stress kinase, p38alpha, through MKK3/6-independent and -dependent mechanisms. J Biol Chem. 2007;282(37):27020-9. Epub 20070713. doi: 10.1074/jbc.M701108200. PubMed PMID: 17631503.

40.        Kozikowski AP, Gaisina IN, Yuan H, Petukhov PA, Blond SY, Fedolak A, Caldarone B, McGonigle P. Structure-based design leads to the identification of lithium mimetics that block mania-like effects in rodents. possible new GSK-3beta therapies for bipolar disorders. J Am Chem Soc. 2007;129(26):8328-32. Epub 20070607. doi: 10.1021/ja068969w. PubMed PMID: 17552518.

41.        McCarty K, Petukhov PA, Mandal SK, He R, Schlottmann S, Frkizan V, Uren A, Kozikowski AP, Toretsky JA. Novel small molecule inhibitors of akt reduce Ewing's sarcoma cell growth. Pediatr Blood Cancer. 2007;48(6):635-. WOS:000246013900146.

42.        Kozikowski AP, Chellappan SK, Xiao Y, Bajjuri KM, Yuan H, Kellar KJ, Petukhov PA. Chemical medicine: novel 10-substituted cytisine derivatives with increased selectivity for alpha4beta2 nicotinic acetylcholine receptors. ChemMedChem. 2007;2(8):1157-61. doi: 10.1002/cmdc.200700073. PubMed PMID: 17530728.

43.        Qin Z, Kastrati I, Chandrasena RE, Liu H, Yao P, Petukhov PA, Bolton JL, Thatcher GR. Benzothiophene selective estrogen receptor modulators with modulated oxidative activity and receptor affinity. J Med Chem. 2007;50(11):2682-92. Epub 20070510. doi: 10.1021/jm070079j. PubMed PMID: 17489582.

44.        Yuan H, Petukhov PA. Improved 3D-QSAR CoMFA of the dopamine transporter blockers with multiple conformations using the genetic algorithm. Bioorg Med Chem Lett. 2006;16(24):6267-72. Epub 20061005. doi: 10.1016/j.bmcl.2006.09.037. PubMed PMID: 17027270.

45.        Yuan H, Petukhov PA. Computational evidence for the ligand selectivity to the alpha4beta2 and alpha3beta4 nicotinic acetylcholine receptors. Bioorg Med Chem. 2006;14(23):7936-42. Epub 20060821. doi: 10.1016/j.bmc.2006.07.049. PubMed PMID: 16919961.

46.        Kozikowski AP, Gaisina IN, Petukhov PA, Sridhar J, King LT, Blond SY, Duka T, Rusnak M, Sidhu A. Highly potent and specific GSK-3beta inhibitors that block tau phosphorylation and decrease alpha-synuclein protein expression in a cellular model of Parkinson's disease. ChemMedChem. 2006;1(2):256-66. doi: 10.1002/cmdc.200500039. PubMed PMID: 16892358.

47.        Jung M, Velena A, Chen B, Petukhov PA, Kozikowski AP, Dritschilo A. Novel HDAC inhibitors with radiosensitizing properties. Radiat Res. 2005;163(5):488-93. doi: 10.1667/rr3345. PubMed PMID: 15850409.

48.        Wei ZL, Xiao Y, Yuan H, Baydyuk M, Petukhov PA, Musachio JL, Kellar KJ, Kozikowski AP. Novel pyridyl ring C5 substituted analogues of epibatidine and 3-(1-methyl-2(S)-pyrrolidinylmethoxy)pyridine (A-84543) as highly selective agents for neuronal nicotinic acetylcholine receptors containing beta2 subunits. J Med Chem. 2005;48(6):1721-4. doi: 10.1021/jm0492406. PubMed PMID: 15771418.

49.        Chen B, Petukhov PA, Jung M, Velena A, Eliseeva E, Dritschilo A, Kozikowski AP. Chemistry and biology of mercaptoacetamides as novel histone deacetylase inhibitors. Bioorg Med Chem Lett. 2005;15(5):1389-92. doi: 10.1016/j.bmcl.2005.01.006. PubMed PMID: 15713393.

50.        Wei ZL, Petukhov PA, Bizik F, Teixeira JC, Mercola M, Volpe EA, Glazer RI, Willson TM, Kozikowski AP. Isoxazolyl-serine-based agonists of peroxisome proliferator-activated receptor: design, synthesis, and effects on cardiomyocyte differentiation. J Am Chem Soc. 2004;126(51):16714-5. doi: 10.1021/ja046386l. PubMed PMID: 15612696.

51.        Yuan H, Kozikowski AP, Petukhov PA. CoMFA study of piperidine analogues of cocaine at the dopamine transporter: exploring the binding mode of the 3 alpha-substituent of the piperidine ring using pharmacophore-based flexible alignment. J Med Chem. 2004;47(25):6137-43. doi: 10.1021/jm049544s. PubMed PMID: 15566285.

52.        Pearce LV, Petukhov PA, Szabo T, Kedei N, Bizik F, Kozikowski AP, Blumberg PM. Evodiamine functions as an agonist for the vanilloid receptor TRPV1. Org Biomol Chem. 2004;2(16):2281-6. Epub 20040727. doi: 10.1039/B404506H. PubMed PMID: 15305207.

53.        Petukhov PA, Zhang J, Wang CZ, Ye YP, Johnson KM, Kozikowski AP. Synthesis, molecular modeling, and biological studies of novel piperidine-based analogues of cocaine: evidence of unfavorable interactions proximal to the 3alpha-position of the piperidine ring. J Med Chem. 2004;47(12):3009-18. doi: 10.1021/jm0303296. PubMed PMID: 15163183.

54.        Castillo SS, Brognard J, Petukhov PA, Zhang C, Tsurutani J, Granville CA, Li M, Jung M, West KA, Gills JG, Kozikowski AP, Dennis PA. Preferential inhibition of Akt and killing of Akt-dependent cancer cells by rationally designed phosphatidylinositol ether lipid analogues. Cancer Res. 2004;64(8):2782-92. doi: 10.1158/0008-5472.can-03-1530. PubMed PMID: 15087394.

55.        Kozikowski AP, Zhang J, Nan F, Petukhov PA, Grajkowska E, Wroblewski JT, Yamamoto T, Bzdega T, Wroblewska B, Neale JH. Synthesis of urea-based inhibitors as active site probes of glutamate carboxypeptidase II: efficacy as analgesic agents. J Med Chem. 2004;47(7):1729-38. doi: 10.1021/jm0306226. PubMed PMID: 15027864.

56.        Li Q, Jin C, Petukhov PA, Rukavishnikov AV, Zaikova TO, Phadke A, LaMunyon DH, Lee MD, Keana JF. Synthesis of well-defined tower-shaped 1,3,5-trisubstituted adamantanes incorporating a macrocyclic trilactam ring system. J Org Chem. 2004;69(4):1010-9. doi: 10.1021/jo035640+. PubMed PMID: 14961648.

57.        Li Q, Rukavishnikov AV, Petukhov PA, Zaikova TO, Jin C, Keana JF. Nanoscale tripodal 1,3,5,7-tetrasubstituted adamantanes for AFM applications. J Org Chem. 2003;68(12):4862-9. doi: 10.1021/jo026923p. PubMed PMID: 12790592.

58.        Wei ZL, Petukhov PA, Xiao Y, Tuckmantel W, George C, Kellar KJ, Kozikowski AP. Synthesis, nicotinic acetylcholine receptor binding affinities, and molecular modeling of constrained epibatidine analogues. J Med Chem. 2003;46(6):921-4. doi: 10.1021/jm025613w. PubMed PMID: 12620069.

59.        Kozikowski AP, Nowak I, Petukhov PA, Etcheberrigaray R, Mohamed A, Tan M, Lewin N, Hennings H, Pearce LL, Blumberg PM. New amide-bearing benzolactam-based protein kinase C modulators induce enhanced secretion of the amyloid precursor protein metabolite sAPPalpha. J Med Chem. 2003;46(3):364-73. doi: 10.1021/jm020350r. PubMed PMID: 12540236.

60.        Li Q, Rukavishnikov AV, Petukhov PA, Zaikova TO, Keana JF. Nanoscale 1,3,5,7-tetrasubstituted adamantanes and p-substituted tetraphenyl-methanes for AFM applications. Org Lett. 2002;4(21):3631-4. doi: 10.1021/ol026495+. PubMed PMID: 12375905.

61.        Woolverton WL, Ranaldi R, Wang Z, Ordway GA, Paul IA, Petukhov P, Kozikowski A. Reinforcing strength of a novel dopamine transporter ligand: pharmacodynamic and pharmacokinetic mechanisms. J Pharmacol Exp Ther. 2002;303(1):211-7. doi: 10.1124/jpet.102.037812. PubMed PMID: 12235253.

62.        Petukhov PA, Zhang J, Kozikowski AP, Wang CZ, Ye YP, Johnson KM, Tella SR. SAR studies of piperidine-based analogues of cocaine. 4. Effect of N-modification and ester replacement. J Med Chem. 2002;45(15):3161-70. doi: 10.1021/jm0200153. PubMed PMID: 12109901.

63.        Wei ZL, Sakamuri S, Petukhov PA, George C, Lewin NE, Blumberg PM, Kozikowski AP. Synthesis and modeling study of (2S,5R,6R)- and (2S,5R,6S)-6-hydroxy- 8-(1-decynyl)-benzolactam-V8 as protein kinase C modulators. Org Lett. 2002;4(13):2169-72. doi: 10.1021/ol026013u. PubMed PMID: 12074659.

64.        Petukhov PA, Zhang M, Johnson KJ, Tella SR, Kozikowski AP. Sar studies of piperidine-based analogues of cocaine. Part 3: oxadiazoles. Bioorg Med Chem Lett. 2001;11(16):2079-83. doi: 10.1016/s0960-894x(01)00379-1. PubMed PMID: 11514143.

65.        Petukhov PA, Bizyaev SN, Tkachev AV. Synthesis of alpha-amino oximes and bis-alpha-amino oximes from the monoterpene hydrocarbons 3-carene and alpha-pinene and alpha,omega-diamines. Russ Chem B+. 2001;50(11):2106-12. doi: Doi 10.1023/A:1015097200993. WOS:000175056400024.

66.        Petukhov PA, Bagryanskaya IY, Gatilov YV, Tkachev AV. Novel terpene-based chiral bis-alpha-aminooximes and the corresponding macrocycles: X-ray structure of a ring-fused 5,7-dioxa-1,4,8,11-tetraazacyclotrideca-3,8-diene derivative. Mendeleev Commun. 2000(6):209-10. WOS:000166410100002.

67.        Maksakov VA, Kirin VP, Petukhov PA, Rybalova TV, Gatilov YV, Tkachev AV. Syntheses and crystal structure of bridged Os-3-clusters with chiral 3-carane-type ligands. J Organomet Chem. 2000;604(1):1-6. doi: Doi 10.1016/S0022-328x(00)00153-4. WOS:000088339500001.

68.        Kirin VP, Maksakov VA, Virovets AV, Petukhov PA, Popov SA, Tkachev AV. Synthesis of optically active hydridocarbonyl triosmium clusters with terpene derivatives as ligands. Molecular structure and absolute configuration of a cluster with a bridging dihydroimidazole ligand. Russ Chem B+. 2000;49(8):1440-7. doi: Doi 10.1007/Bf02495094. WOS:000089808100024.

69.        Rukavishnikov AV, Phadke A, Lee MD, LaMunyon DH, Petukhov PA, Keana JFW. A tower-shaped prototypic molecule designed as an atomically sharp tip for AFM applications. Tetrahedron Lett. 1999;40(35):6353-6. doi: Doi 10.1016/S0040-4039(99)01207-1. WOS:000082199700007.

70.        Maksakov VA, Kirin VP, Virovets AV, Petukhov PA, Tkachev AV. Transformation of diaminocarane on a triosmium cluster. Absolute configuration of a cluster with a bridging imidyl ligand. Mendeleev Commun. 1999(6):213-4. WOS:000084603900001.

71.        Petukhov PA, Tkachev AV. Sodium borohydride in an acetonitrile medium: An efficient reagent for reductive Beckmann type fragmentation of alpha-amino oximes. Tetrahedron. 1997;53(7):2535-50. doi: Doi 10.1016/S0040-4020(96)01142-8. WOS:A1997WJ21100019.

72.        Petukhov PA, Tkachev AV. Synthesis of chiral hexahydrophenazines by treatment of dimeric nitrosochlorides with 1,2-diaminoarenes. Tetrahedron. 1997;53(28):9761-8. doi: Doi 10.1016/S0040-4020(97)00623-6. WOS:A1997XK06200029.

73.        Petukhov PA, Denisov AY, Tkachev AV. Rearrangement of alpha-hydroxylamino oximes to cyclic amidoximes by the action of sodium borohydride. Tetrahedron. 1997;53(7):2527-34. doi: Doi 10.1016/S0040-4020(96)01141-6. WOS:A1997WJ21100018.

74.        Petukhov PA, Tkachev AV. Synthesis of monoterpenic alpha-amino ketones. Mendeleev Commun. 1996(2):64-6. WOS:A1996UJ32500013.

75.        Tkachev AV, Petukhov PA, Konchenko SN, Korenev SV, Fedotov MA, Gatilov YV, Rybalova TV, Kholdeeva OA. Optically-Active Zn-Ii and Pt-Ii Complexes of the 3-Carene Type Alpha-Amino Oxime. Tetrahedron-Asymmetr. 1995;6(1):115-22. doi: Doi 10.1016/0957-4166(94)00366-J. WOS:A1995QF02600033.

76.        Petukhov PA, Tkachev AV. Reductive Beckmann Type Fragmentation of Alpha-Amino Oximes by Sodium-Borohydride - a New Synthetic Pathway to Omega-Amino Nitriles. Synlett. 1993(8):580-. WOS:A1993LU13800015.